Description
JANUVIA® (Sitagliptin): Effective Blood Sugar Management for Type 2 Diabetes
Managing type 2 diabetes requires a comprehensive approach, including medication, diet, and exercise. JANUVIA® (sitagliptin) is a once-daily prescription pill designed to help adults with type 2 diabetes control their blood sugar levels effectively.
What Is JANUVIA®?
JANUVIA® is an oral medication that belongs to the class of drugs known as dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by regulating the levels of insulin your body produces after eating, thereby aiding in blood sugar control.
Key Benefits of JANUVIA®
1. Effective Blood Sugar Control
JANUVIA® helps lower blood sugar levels in adults with type 2 diabetes when used in conjunction with diet and exercise.
2. Convenient Once-Daily Dosage
With a simple once-daily dosing schedule, JANUVIA® fits seamlessly into your daily routine.
3. Low Risk of Hypoglycemia
When used alone, JANUVIA® has a low risk of causing hypoglycemia (low blood sugar), making it a safer option for many patients.
How Does JANUVIA® Work?
JANUVIA® enhances the body’s own ability to control blood sugar levels by inhibiting the DPP-4 enzyme. This inhibition increases the levels of incretin hormones, which help to:
- Increase insulin release after meals.
- Decrease the amount of sugar produced by the liver.
Usage and Dosage
Recommended Dosage
The typical dose of JANUVIA® is 100 mg once daily, with or without food. However, your healthcare provider may adjust your dose based on your kidney function.
Important Considerations
- Kidney Function: Dosage adjustments may be necessary for patients with renal impairment.
- Combination Therapy: JANUVIA® can be used alone or in combination with other medications, such as metformin or insulin, as prescribed by your healthcare provider.
Safety Information
Common Side Effects
- Upper respiratory tract infection
- Headache
- Nasopharyngitis (stuffy or runny nose and sore throat)
Serious Side Effects
- Pancreatitis: Inflammation of the pancreas.
- Heart Failure: Monitor for signs and symptoms.
- Kidney Problems: Including acute renal failure.
If you experience any severe side effects, contact your healthcare provider immediately.
Recent Sales Statistics
JANUVIA® has been a significant contributor to Merck’s pharmaceutical sales. In 2022, combined sales of JANUVIA® and JANUMET® (sitagliptin/metformin) reached approximately $4.513 billion.
Frequently Asked Questions about JANUVIA®
1. What is JANUVIA® used for?
JANUVIA® is used to help lower blood sugar levels in adults with type 2 diabetes, in combination with diet and exercise.
2. How should I take JANUVIA®?
Take JANUVIA® exactly as prescribed by your healthcare provider, typically once daily, with or without food.
3. Can JANUVIA® be used with other diabetes medications?
Yes, JANUVIA® can be used alone or in combination with other medications, such as metformin or insulin, as directed by your healthcare provider.
4. What should I do if I miss a dose?
If you miss a dose of JANUVIA®, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time.
5. Are there any dietary restrictions while taking JANUVIA®?
While taking JANUVIA®, it’s important to follow a balanced diet as advised by your healthcare provider to help control your blood sugar levels.
JANUVIA® (sitagliptin) offers an effective and convenient option for managing blood sugar levels in adults with type 2 diabetes. Always consult your healthcare provider to determine if JANUVIA® is the right choice for you.
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